פרקטיקה מבוססת ראיות: הערכת ראיות 2

The Grading of Recommendations Assessment, Development and Evaluation (short GRADE) Working Group began in the year 2000 as an informal collaboration of people with an interest in addressing the shortcomings of present grading systems in health care. The working group has developed a common, sensible and transparent approach to grading quality of evidence and strength of recommendations. Many international organizations have provided input into the development of the approach and have started using it.

These online learning modules are designed to help guideline developers and authors of systematic reviews learn how to use the GRADE approach to grade the evidence in systematic reviews, to create Summary of Findings Tables and GRADE Evidence Profiles, and move from evidence to making recommendations.

This software allows you to create a Summary of Findings (SoF) table. It can retrieve data of the systematic review and meta-analyses from a Review Manager 5 file, combine these data with user-entered data, and then export a Summary of Findings table ready for import into Review Manager 5. It performs many of the calculations necessary to present the key results of systematic reviews in a table format and guides users through the process of grading the quality of the evidence using the GRADE approach.

UpToDate has adopted the GRADE approach with only a minor modification. The grading scheme classifies recommendations as strong (Grade 1) or weak (Grade 2), according to the balance between benefits, risks, burden, and cost, and the degree of confidence in estimates of benefits, risks, and burden. The system classifies quality of evidence (as reflected in confidence in estimates of effects) as high (Grade A), moderate (Grade B), or low (Grade C) according to factors that include the risk of bias, precision of estimates, the consistency of the results, and the directness of the evidence.

This tutorial was created for UpToDate authors, section editors, and peer reviewers, but it is available for anyone who wants to learn about GRADE. We expect it will take you about 30 minutes to complete.

This section describes the CTFPHC process for developing its evidence reviews.
Canadian Task Force on Preventive Health Care - Procedure Manual

McMaster PLUS (Premium LiteratUre Service) is a database created by the McMaster Health Knowledge Refinery (HKR). Articles are continuously selected from the current medical literature via our Critical Appraisal Process (CAP) that identifies studies and systematic reviews that are scientifically strong; articles that meet our scientific criteria are then rated by frontline clinicians for relevance and newsworthiness through the McMaster Online Rating of Evidence (MORE) system. The PLUS process is described in detail on the website.